Cloning

Cloning Neanderthals?

November 26, 2008

Neanderthal175 I don’t know about you, but I was absolutely dumbfounded a while back by a news article reporting that a California woman had spent $50,000 to have a South Korean company, RNL Bio, clone skin cells taken from her dead pit bull, Booger, to produce five genetic replicas of him. OK, they are cute, as this photo  illustrates. But not any more so than Rachel, a young female bull terrier-American Staffordshire terrier mix who is currently available for adoption in Los Angeles from Dogs Without Borders. The same could be said for any of about eight zillion other members of the bully breed who are languishing in animal control lockups across the U.S. as you read this. I can think of potentially beneficial — or least, justifiable — applications of cloning technology, but churning out puppies isn’t one of them. We’ve already got more than enough. (FYI, here’s the Humane Society of the United States’ position on the issue of pet cloning.)

If we’re going to clone something, why not pick something in much rarer supply? How about … a caveman?

Continue reading >

Should Humans Be Cloned?

February 01, 2008

Humansclonedidea If you’re uneasy about the FDA’s recent decision that meat and milk from cloned animals and their offspring is safe for human consumption, this story is really going to rock your world. Stemagen, a La Jolla, Calif.-based private-sector stem cell research company, has announced that its scientists have for the first time created a human embryo by cloning adult cells through somatic cell nuclear transfer, the same process used to create cloned animals.

You may be thinking that you’ve heard this before, because you have. Back in 2004, South Korean scientists announced that they not only had created a human embryo via cloning but had successfully extracted stem cells from it. After their work could not be replicated, lead scientist Hwang Woo-Suk was forced to admit that the results had been fabricated.

As a result, Stemagen seems to have taken extra care to document its findings, an article accepted by the peer-reviewed scientific journal Stem Cells. The researchers had an independent lab do DNA fingerprinting to prove that the embryos were true clones of the cells from which they originated.

Stemagen chief executive Dr. Samuel H. Wood, who doubled as a donor of the cells from which some of the embryos were cloned, describes the project as “a critical milestone in the development of patient-specific embryonic stem cells for human therapeutic use, potentially including developing treatments for Parkinson’s, Alzheimer’s and other degenerative diseases.”

But not everybody is going to hail this as a breakthrough. The idea of creating an embryonic clone of a person in order to harvest stem cells — and then discarding the clone — is abhorrent to opponents of most conventional embryonic stem cell research, who consider the destruction of an embryo to be murder. Even those who aren’t outright opposed raise some potentially troubling questions. For example, bioethicist and blogger Arthur Caplan writes:

In the paper announcing the breakthrough, the authors note that they got three out of 25 attempts at clones to turn into human clone embryos. That is a success rate of about 10 percent. Even if that success rate improves in the future, it still means that six or more eggs are going to be required for a researcher to make a stem cell from a clone made from the DNA of one of your own cells.

Where will hundreds of thousands of eggs come from when hundreds of thousands seek cures? Will we pay poor women to create them? Egg-farming, using powerful drugs with serious risks, may not be the most humane way to ask a poor woman to earn a living.

And although this obviously isn’t the Stemagen scientists’ intention, some undoubtedly worry that the process will be used to produce human infants who are perfect genetic duplicates of a cell donor. (It may already have happened, if you buy the 2004 claim of a mysterious outfit named Clonaid that it actually had produced 13 cloned human children; skeptical New York Times journalists pointed out that the company was founded by the leader of a sect that preaches space travelers originally populated Earth through cloning.) If such cloning proved feasible and the process was widely available, would people resort to cloning in an attempt to make themselves (or at least their genetic blueprint) immortal? Or would companies obtain cell samples from the most productive workers and use them to create a generation of super employees who would bump those of us with conventional origins into the unemployment line? Would human clones have the same civil rights as their progenitors? What if terrorists used cloning to create an endless supply of suicide bombers? That all may sound crazy,  but crazy things sometimes happen.

What’s your opinion on human cloning? Say your piece here.

Should Humans Use Cloned Animals for Food?

January 11, 2008

Ideacloned011108 You vegans out there probably don’t give a hill of beans about the Washington Post’s recent revelation that the U.S. Food and Drug Administration is about to say that it’s OK for humans to eat meat and use dairy products from cloned animals. But the omnivorous masses, the ones who pick one fast-food joint over another because the patties are supposedly fresh rather than frozen, may get a little uneasy at the prospect of chomping into a double burger with cheese produced by somatic cell transfer, rather than the old fashioned way.

Scientists started cloning animals back in 1996, when Dolly the sheep was produced in Scotland. But for years, U.S. regulators were cautious about allowing clones to become part of the U.S. food supply. However, based a 2002 National Academy of Sciences report and additional findings from researchers in the U.S. and Japan in 2005, the FDA issued a draft risk assessment in 2006 that meat and milk from clones of adult cattle, pigs and goats, and their offspring are as safe to eat as food from conventionally bred animals. But consumer and health activists remain unconvinced. In December 2007, the U.S. Senate passed an amendment to the 2007 farm bill by Sen. Arlen Specter, R-Pa., and Sen. Barbara Mikulski, D-Md., that would require more government study of clones’ safety, but it’s unclear whether that restriction will make it into the final bill. If it doesn’t, the FDA’s approval would mean that meat and milk from the offspring of clones — and eventually, as the cost of the technology drops, from clones themselves — could start appearing in supermarkets and on restaurant menus sometime in the near future.

Proponents of animal cloning see the brouhaha as an unnecessary one. "Thousands of data points, hundreds of peer-reviewed journal articles and two reviews by the National Academies have all said the same thing," Mark Walton, president of ViaGen, an Austin, Texas-based animal cloning company, told the Post. "There is nothing left to review." David Faber, president of TransOva, an Iowa-based cloning outfit, insisted to the Des Moines Register that “there is no food safety issue with clones.” The Los Angeles Times actually went so far as to sponsor a taste test at an upscale L.A. eatery, in which six diners were asked to tell the difference between cloned and conventional beef. (They couldn’t.)

The rationale behind cloning cattle is that animals with the best genetic makeup to produce tasty meat or milk could be duplicated again and again. In theory, that ultimately would make the finest quality sirloin burgers or porterhouse steaks available cheaply to everyone.

Scientific American points out that the cattle industry has long employed a process called budding, in which the undifferentiated cells in a fertilized cow egg are separated, so that they grow into hundreds of artificially induced siblings (“natural clones,” as the magazine calls them).

None of this seems to have persuaded the public; a recent Pew poll found that six out of 10 Americans regarded the notion of eating cloned beef as, well, kind of icky. Consumers Union points out that many clones suffer from severe deformities, and those that survive often have weak immune systems and require large doses of antibiotics to survive. “At the very least, raising clones will necessitate greater use of antibiotics on food animals, worsening the existing problem of antibiotic-resistant bacteria that can infect and sicken humans,” CU testified on behalf of proposed California legislation that would require special labeling identifying food that came from clones.

The Union of Concerned Scientists wrote in its public comments on the FDA’s draft risk assessment:

Animal cloning remains a technology in its early stages that still produces primarily debilitated and physiologically impaired animals. Regarding the relatively few animals that survive to adulthood and appear to be normal, there are sufficient differences between clones and non-clones to conclude that they are not normal, or at least not normal enough to conclude that subtle changes do not pose health risks. Although the possibility of such effects is not great, because milk and meat are so widely consumed in the United States, these deserve to be addressed experimentally in well-defined consumption and safety studies done in all species and breeds headed for the market on animals at the ages they are likely to be consumed.

So are you ready for a T-bone clone, or does the idea of “Frankenfood” gross you out? Express your opinion below.


Patrick J. Kiger has written for print publications ranging from GQ to the Los Angeles Times Magazine, and is the co-author of two books, Poplorica: A popular history of the fads, mavericks, inventions and lore that shaped modern America," and Oops: 20 life lessons from the fiascoes that shaped America. For more of his work, check out his web site, www.patrickjkiger.com.
Advertisement

Recent Comments

 
SITE SEARCH
SUBSCRIBE TO OUR NEWSLETTERS
CREDITS Photos: iStockphoto | Getty Images | AP | Wikipedia | DCL |
DISCOVERY SITES Discovery Channel / TLC / Animal Planet / Discovery Health / Science Channel / Planet Green / Discovery Kids / Military Channel /
Investigation Discovery / HD Theater / Turbo / FitTV / HowStuffWorks / TreeHugger / Petfinder / PetVideo / Discovery Education
SHOP Toys / Games / Telescopes / DVD Sets / Planet Earth DVD Sets / Gift Ideas
CUSTOMER SERVICE Viewer Relations / Free Newsletters / RSS /
CORPORATE Discovery Communications, Inc / Advertising / Careers @ Discovery / Privacy Policy / Visitor Agreement
ATTENTION! We recently updated our privacy policy. The changes are effective as of Tuesday, October 30, 2007. To see the new policy, click here. Questions? See the policy for the contact information.